News Medical: Genotype-guided warfarin dosing linked to reduced risk of adverse events Daily warfarin dosing requirements clearly decrease with advancing age. To examine the relation between age and warfarin dosing, researchers analyzed data from 101 U.S. sites that were participating ...
The New England Journal of Medicine: A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing The clinical utility of genotype-guided (pharmacogenetically based) dosing of warfarin has been tested only in small clinical trials or observational studies, with equivocal results. We randomly ... Using genetic testing to help personalize doses of warfarin therapy given to patients undergoing elective orthopedic surgery appears to lower the risk of combined adverse events compared with ... Utility (or quality-of-life) scores for the different health states were used to calculate the difference in quality-adjusted life-years (QALYs) between the standard and the genotype-guided dosing ...
dosing of warfarin, MedPage Today: Patients Can Manage Their Own Warfarin Just Fine, Study Suggests Patient self-management of warfarin is endorsed by U.S. guidelines, but an in-clinic approach remains the norm due to clinician reluctance and other barriers. Among patients who agreed to make their ...
